BACKGROUND: Age-related macular degeneration (AMD) is a common cause of blindness worldwide. Neovascular AMD (nAMD) is an advanced form of the disease, in which excess …
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Serum BNP may be Inversely Correlated with Thyroid Hormone Sufficiency in Cardiac Tissues
BACKGROUND: Cardiac re-expression of fetal genes in patients with heart failure (HF) suggests the presence of low cardiac tissue thyroid hormone (TH) function. However, serum …
Read moreCould Low-Dose Naltrexone be a Viable Option for Some Psoriasis Patients?
OBJECTIVE: To determine the efficacy of low dose naltrexone in the patients of psoriasis. STUDY DESIGN: Non-randomised clinical trial. PLACE AND DURATION OF STUDY: Department …
Read moreOlanzapine may Alleviate Nausea and Vomiting Associated with Advanced Cancer
IMPORTANCE: Nausea and vomiting, unrelated to chemotherapy, can be substantial symptoms in patients with advanced cancer. OBJECTIVE: To evaluate the utility of olanzapine for treating …
Read moreCould Post-Exposure Application of Imiquimod Cream at the Inoculation Site Prevent Systemic Infection of Mosquito-Borne Viruses?
ABSTRACT: Arthropod-borne viruses (arboviruses) are important human pathogens for which there are no specific antiviral medicines. The abundance of genetically distinct arbovirus species, coupled with …
Read moreIf You Need to Prescribe an Antidepressant for Major Depressive Disorder in the Elderly, SSRIs are Probably the Safer Options
OBJECTIVES: To assess adverse effects of pharmacologic antidepressants for treatment of major depressive disorder (MDD) in adults 65 years of age or older. DESIGN: Systematic review …
Read moreBe Careful When Adding Allopurinol in Patients with Heart Failure
ABSTRACT: Several trials have been completed in patients with heart failure (HF) treated with uric acid (UA)-lowering agents with inconsistent results. We aimed to investigate …
Read moreCould Rapamcin be Used in the Prevention of Alzheimer’s Disease in the Near Future?
ABSTRACT: Cerebrovascular dysfunction and cognitive decline are highly prevalent in aging, but the mechanisms underlying these impairments are unclear. Cerebral blood flow decreases with aging …
Read moreNow We Have a Better Understanding Why Beta-Blockers May Cause Psoriasis Exacerbation in Some People
ABSTRACT: Oxidative stress and Th17 cytokines are important mediators of inflammation. Treatment with beta-adrenoceptor (ADRB) antagonists (beta-blockers) is associated with induction or aggravation of psoriasis-like …
Read moreSitagliptin Looks Promising as Potential Treatment for Women Suffering from Recurrent Pregnancy Loss
BACKGROUND: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of …
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