Main Menu 1. The Use of GLP-1 Receptor Agonists is Associated with an Increased Risk of Thyroid Cancer OBJECTIVE: To determine whether use of glucagon-like …Read more
Category: Drug Whisperer
Could Intravenous Magnesium and Potassium Improve the Chance of Spontaneous Conversion for A. Fib Patients in ER?
IMPORTANCE: Whether the simultaneous intravenous administration of potassium and magnesium is associated with the probability of spontaneous conversion to sinus rhythm (SCV) in the acute treatment …Read more
Should We Consider Giving Metformin to Atrial Fibrillation Patients?
ABSTRACT: Effective drugs for atrial fibrillation (AF) are lacking, resulting in significant morbidity and mortality. This study demonstrates that network proximity analysis of differentially expressed genes …Read more
Metformin & Testosterone, either used Individually or in Combination Improves Insulin Resistance in Obese Men with Low Testosterone
BACKGROUND: Men with obesity tend to be insulin resistant and often have low-normal testosterone concentrations. We conducted a clinical trial aimed to evaluate potential therapeutic strategies …Read more
Metformin Use and Testosterone Replacement Therapy are Independently and Jointly Associated with Reduced Risks of Prostate and Colorectal Cancer Diagnoses
BACKGROUND: The independent and joint association of metformin and testosterone replacement therapy (TTh) with the incidence of prostate, colorectal, and male breast cancers remain poorly …Read more
The Risks of Proton Pump Inhibitor Prescription Should be Carefully Evaluated in Cirrhosis Patients
BACKGROUND & AIMS: The impact of proton pump inhibitory (PPI) medications on adverse outcomes in cirrhosis remains controversial. We aimed to evaluate the association between PPI …Read more
Patients with a History of Differentiated Thyroid Cancer Probably Should Avoid the Use of Desiccated Thyroid Extract
ABSTRACT: Thyroglobulin (Tg) monitoring is the biochemical standard for surveillance of recurrent differentiated thyroid cancer (DTC). Several assays are available to quantify Tg levels: immunometric assay …Read more
Regular Intake of Soy Isoflavones, But Not Green Tea Extract, May Reduce The Bioavailability of Simvastatin In Some Patients
OBJECTIVES: Green tea and soy products are extensively consumed by many people and they may influence the activity of drug metabolizing enzymes and drug transporters to …Read more
Could Colchicine Have A Role In Reducing Mortality In Acute Decompensated Heart Failure Patients?
BACKGROUND: Gout is a common comorbidity in heart failure (HF) patients and is frequently associated with acute exacerbations during treatment for decompensated HF. Although colchicine is …Read more
Fecal Microbiota Transplant May Improve Melanoma Patients’ Response to Anti-PD-1 Therapy
ABSTRACT: Anti–programmed cell death protein 1 (PD-1) therapy provides long-term clinical benefits to patients with advanced melanoma. The composition of the gut microbiota correlates with anti–PD-1 …Read more